Tuesday, February 25, 2014

Pharmacological advances that have occurred in the last year regarding petticoat lane market liver


Pharmacological advances that have occurred in the last year regarding petticoat lane market liver will in a few years almost completely eradicate the hepatitis C. They have gathered several experts said at a press conference under the XXXIX Annual Conference of the Spanish Association for the Study of the Liver (AEEH), which brings together more than 600 hepatologist throughout Spain.
In fact, new antiviral drugs have shown to cure more than 90 percent of hepatitis C patients and, consequently, allow the reduction of other liver diseases petticoat lane market that arise from the natural evolution of this virus, such as cirrhosis or liver cancer.
José Luis Calleja, Secretary General and member of AEEH Gastroenterology and Hepatology, University Hospital Puerta del Ferro Majadahonda, explained that, "until ten years ago, the treatment of hepatitis C was made by combining two drugs, a weekly injection of interferon along with ribavirin taken daily to cure 40 to 45 percent of patients were infected with certain types of hepatitis C, genotype 1, which is the most common in Spain. "
In 2011 they released two new drugs, telaprevir and boceprevir, two protease inhibitors that increase the cure rate of patients with genotype 1, from 40 to 70 percent.
But the European Medicines petticoat lane market Agency (EMEA) has just approved a new drug, sofosbuvir, petticoat lane market an NS5A inhibitor that, through its combination with other drugs that are still in the approval process, as simeprevir and daclatasvir is be available for the first time, an oral treatment to cure hepatitis C without the administration of interferon injection which can achieve "healing rates of about 90 percent is'assolirà almost no effect side, "said Calleja.
Most of these drugs can be administered for the treatment of different genotypes of hepatitis C, something unattainable until now. The duration of treatment is also one of the improvements that will bring these new drugs, since his administration will twelve months to half (six months) or even three months in some cases.
Given this promising paradigm, experts claim the need to develop a national strategy to ensure the equal access of these new drugs, since, in addition to saving lives, drugs have proven to be cost-effective. "We want to make the government realize that these treatments is an investment and not an expense, avoiding high costs subsequent cancer, petticoat lane market cirrhosis, transplantation, petticoat lane market etc.., Which are far more expensive petticoat lane market than these," said Calleja.
Meanwhile, the president of the AEEH, Jaume Bosch, scientific director of CIBER Hepatic petticoat lane market and Digestive petticoat lane market and member of the Hepatology Service of the Hospital Clinic of Barcelona, said that "these drug treatments will be the market with a high cost and, therefore, probably at the beginning implemented in patients who are in more advanced stages, ie, those who could die in the next two years if not treated before " , and adds that "although the economic impact of treating all patients could be very high, there are preliminary studies that show that it is more cost-effective to treat patients petticoat lane market from the time of diagnosis."
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