Hepatitis C can be cured only between three and six months New oral drugs allow to cure more than 90% of cases. The Spanish Association for the Study of the liver (AEEH) calls for a national strategy to address implementation.
Thanks estate sale finder to the emergence of new oral therapies, hepatitis C could be eradicated. In Spain, estate sale finder hepatitis C affects more than 900,000 people and about 70% of those who suffer unknown. estate sale finder It is an infectious estate sale finder disease that causes liver transplantation, cirrhosis and liver cancer.
"Until ten years, from 2002 to 2011, the treatment of hepatitis C was made by combining two drugs, a weekly injection of interferon with ribavirin daily decision," said Dr. José Luis Calleja Secretary General of the Annual Conference of the Spanish Association for the Study of the Liver (AEEH) and member of the Gastroenterology and Hepatology, University Hospital Puerta del Ferro Majadahonda. "This treatment cured between 40% and 45% of patients who were infected by certain types of hepatitis C, genotype 1, which is the most common in Spain."
But in 2011 they released two new drugs, telaprevir and boceprevir, which are protease inhibitors. Thanks estate sale finder to these drugs cure rate increased from 40% to 70% in patients with genotype 1. "The problem is that this drug, as it is an interferon-based therapy, there is a percentage of patients who, for various reasons, such as poor tolerance or other contraindications, may not benefit from treatment," says Dr Calleja.
A new milestone presents this year thanks to the emergence of another drug, the sofosbuvir (approved by the European Medicines estate sale finder Agency), a NS5A inhibitor. When combined with simeprevir and daclatasvir (in approval process in Europe, already approved in the United States) orally can cure hepatitis C without the administration of interferon estate sale finder injection.
"Through this new treatment, achieve cure rates of about 90%, when before we were in 70% and, most importantly, succeed in shorter periods, almost no side effects, and they can be applied to a higher percentage of infected patients, so that win applicability in the treatment, in terms of comfort and lasting side effects as well as efficacy, "says Dr. Alley.
On the availability of drugs, the president of the AEEH Dr. James Bosch, scientific director of CIBER Hepatic and Digestive Diseases and a member of Hepatology Service of the Hospital Clinic of Barcelona, said that "these new drugs will treatment to be launched with a high cost and, therefore, probably estate sale finder at the beginning implemented in patients who are in more advanced stages, ie, those who could die in the next two years if not dealt with before, "adding that," although estate sale finder the economic impact of treating all patients could be very high, there are preliminary studies that show that it is more cost-effective to treat patients from the time of diagnosis. "
Both experts have pointed winged it is important to have a national strategy to ensure access estate sale finder of these drugs in all regions, and that physicians should be involved in designing the most appropriate strategy for implementation.
Detection of hepatitis C is done with a simple blood test that is available at any health estate sale finder center in Spain. "There are some alternative saliva test, but are not currently approved in Spain, it is likely that they can be available in a short time," says Dr. Alley, which insists that it is important to diagnose patients who have some time risk factor. "This disease occurs particularly in people who have had blood transfusions before the year 92, who had sex risk with piercing or tattoos done in a few recommended places that have history of intravenous drug addiction , and major surgeries in the past, as well as those patients who have the
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